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Clinical and Translational Medicine

Translational Medicine_121521A
[Translational Medicine - Monash University]

- Overview

Clinical and Translational Medicine focuses on the bench to bedside approach, favoring studies and clinical observations which generate hypotheses and questions relevant to the patient and disease, and guide the investigations of cellular and molecular medicine.

Translational medicine (TM) (often referred to as translational science, of which it is a form) is defined by the European Society for Translational Medicine (EUSTM) as "an interdisciplinary branch of the biomedical field supported by three main pillars: benchside, bedside, and community".

The goal of TM is to combine disciplines, resources, expertise, and techniques within these pillars to promote enhancements in prevention, diagnosis, and therapies. Accordingly, translational medicine is a highly interdisciplinary field, the primary goal of which is to coalesce assets of various natures within the individual pillars in order to improve the global healthcare system significantly.


- Translational Research

Translational medicine (TM), also called translational medical science, preclinical research, evidence-based research, or disease-targeted research, area of research that aims to improve human health and longevity by determining the relevance to human disease of novel discoveries in the biological sciences. 

TM is a rapidly growing discipline in biomedical research and aims to expedite the discovery of new diagnostic tools and treatments by using a multi-disciplinary, highly collaborative, "bench-to-bedside" approach. Within public health, TM is focused on ensuring that proven strategies for disease treatment and prevention are actually implemented within the community. 

TM seeks to coordinate the use of new knowledge in clinical practice and to incorporate clinical observations and questions into scientific hypotheses in the laboratory. Thus, it is a bidirectional concept, encompassing so-called bench-to-bedside factors, which aim to increase the efficiency by which new therapeutic strategies developed through basic research are tested clinically, and bedside-to-bench factors, which provide feedback about the applications of new treatments and how they can be improved. TM facilitates the characterization of disease processes and the generation of novel hypotheses based on direct human observation.


- Theme Topics

 Clinical and Translational Medicine specializes in several theme topics:

  • Clinical studies of drugs and devices
  • Target-based drug discovery and development
  • Clinical bioinformatics
  • Clinical trans-omics
  • Single-cell biomedicine.
  • Stem cell biology and therapy
  • Clinical genomics



[More to come ...]


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